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Preimplantation Genetic Diagnosis (PGD)

Preimplantation Genetic Diagnosis (PGD)

Preimplantation genetic diagnosis is carried out for couples who are at a high risk for various genetic disorders. The steps involved in PGD are:

  • Hormonal stimulation and oocyte retrieval
  • IVF/ICSI and fertilization
  • Embryo biopsy at the 8-cell stage: At the 8-cell stage, the embryo is totipotent. Hence, the biopsy of 1-2 blastomeres does not affect further growth of the embryo.
  • Genetic analysis by FISH technique
  • Transfer of normal embryos
PGD showing normal blastomere

The entire process of genetic analysis is completed within a day and chromosomally  normal embryos are transferred.

 
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